https://nutrioplongevity.com/blogs/news/the-four-cellular-horsemen-pqq-coq10-nmn-and-nadh
I’ve been meaning to blog about my new Nootropics stack for ages.
I’ve moved through & out of most of my magic sidebar, all that are still listed served me well at various stages. But I’ve cleared the deck as I wanted to check out these 3 high performers of repute that are especially recommended for older people & those wanting improved cognitive performance whilst protecting themselves from dementia, Alzheimer’s etc, the risk of which is escalated with all forms of long term mental & nervous system illness.
The linked product article calls this stack the 4 horsemen but actually NMN is a precursor to NAD+ in its own right, as is NADH, I think the 2 different versions are popular because they use different pathways in the brain & are synergistic in their own right. I noticed Dr Mercola recommended straight up B3 Niacinamide itself recently to nearly everyone, for a range of metabolic, anti-aging & neurology enhancing purposes so that's a cheaper alternative to both NMN & NADH right there. Check out the difference here.
Anyway, I’ve cheaply sourced my 3 horsemen separately & its a really good combination & I’m really enjoying it, I feel more joined up mentally & I’m having less anxiety so this is a huge win, probably a happy bi-product of it’s neuroprotective aspect. I’m still on a Saffron just one 15mg a day which I definitely feel the benefit of & im on that for the long haul. I briefly used Methylene Blue & had a recovery of some, what I think was retina damage, wtv, it had a really positive effect on my vision which was one of the reasons I was interested in it. I will go back to MB later I feel. (I’ve actually just used it to good affect as an anti microbial on one of my dogs, it has so many uses)
I would say with PQQ, NMN plus Ubiquinol (easier to assimilate CoQ10) I would not deem it necessary for young, fit people or for older people who feel they have optimised their nutrition really well but I’m personally on a mission to restore as much of my neurology as possible that was damaged by not only rolling Bipolar 1 episodes for several decades but endless retraumatisation with all the comorbidities & missed dxs as well as other actual real world traumas.
Here’s a nice article about PQQ
https://drlewisclarke.com/pqq-the-benefits-and-why-your-brain-cells-need-it/
And one about NAD+
https://draxe.com/nutrition/nad-supplement/
& this rat study on Ubiquinol kind of infers why it stacks with PQQ & NMN for brain health
https://link.springer.com/article/10.1134/S1990519X21030111
Screenshot from that:
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